one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity related to bortezomib, a proteasome inhibitor Employed in the therapy of numerous myeloma. Its synthesis or study is crucial for making sure the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the treatment of prostate cancer by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound from the synthesis of imatinib, a drug that targets distinct kinds of most cancers, which includes chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats different cancers including breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their examine is very important for optimizing the output course of action and 5(10)-Triene-3 making certain high purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of to treat breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the remedy of breast cancer. Several intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in managing cancers like ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): 5-Pentafluoropentyl)Thio]Nonyl]-Estra-1 A chemotherapy drug used in the treatment method of colorectal most cancers and compact mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have numerous programs, like antiviral Houses.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind 2 diabetic issues that inhibits the enzyme DPP-four to control blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is associated with the synthesis of varied gluconic acid derivatives, that happen to be Utilized in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication applied to control style two diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).